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Under the leadership of James P. McCulley, M.D., the Department of Ophthalmology at UT Southwestern Medical Center continually trains residents and fellows in cornea and external disease, anterior segment surgery, keratorefractive surgery, retina, glaucoma and pediatric subspecialties. Multiple fellows from Latin America, including the countries of Brazil, Venezuela, Columbia, and Mexico, as well as fellows from Europe and Asia, have graduated and are now practicing in their home countries. Fellowship positions are still routinely available through the fellowship match for qualified applicants from Latin America in cornea and pediatric ophthalmology. Fellowships in other disciplines are considered on an individual basis.
Dr. McCulley’s research interests include over twenty-five years of NIH-supported evaluation into the pathophysiology and therapy of chronic blepharitis and associated ‘dry eyes.’ This work not only has led to an understanding of chronic blepharitis, but to a very thorough understanding of the lipid layer of the tear film which is produced by the Meibomian glands. His work has allowed the development of a model for the structure of the lipid layer of the tear film, and has led to the identification of the biochemical abnormality accounting for the “evaporative dry eye.”
Other research interests have included extensive evaluation of acanthamoeba keratitis. He identified the association between contact lenses and their solutions and the development of acanthamoeba keratitis. He has worked extensively on the pathophysiology and therapy of this severe infectious disease. Dr. McCulley has also had a long-term interest in the tissue culture and transplantation of single layers of corneal endothelium and epithelium. He has had multiple other research interests in the past, including basic and clinical research on chemical injuries of the eye and multiple pharmaceutical trials. Dr. McCulley has published over 350 citable scientific papers, served as Chair of the NEI study Section and Chair of the FDA Ophthalmic Device Panel. He has been the primary investigator on a NEI-funded grant since 1978.
Dr. McCulley is the Medical Coordinator of efforts between the Department of Ophthalmology at the University of Texas Southwestern Medical Center and the Order of St. John to create a junior faculty rotation at the Order of St. John’s Eye Hospital in Jerusalem. He has the lead role in the establishment of a partnership with Prevent Blindness Texas to re-establish, on an annual basis, the “Eye Ball” in Dallas, Texas, an event that funds research in the Department of Ophthalmology. Dr. McCulley has served as an Associate Examiner of the American Board of Ophthalmology and on multiple local, state and national boards, and has been an invited speaker at multiple national and international locations.
Address: Department of Ophthalmology UT Southwestern Medical School 5323 Harry Hines Blvd. 75390-9057 Dallas, Texas USA Teléfono: (1-214) 648-3407 Fax: (1-214) 648-9061 E-mail:
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